What Medical Condition Is Affecting Dave Mustaine’s Hands? Megadeth frontman Dave Mustaine revealed that he’s suffering from Dupuytren’s contracture, a condition that pulls the fingers toward the palm of the hand. Continue reading… Related Posts:Why Dave Mustaine Chose 'Ride the Lightning' for…Dave Mustaine Wants Megadeth to Tour With MetallicaDave Mustaine Discusses Megadeth's Final Studio…Dave Mustaine on Current Relationship With…Dave Mustaine Reveals His Post-Megadeth Dream JobMegadeth's Dave Mustaine Shares a Concern About…See also GN'R Guitarist Makes Shirt in Response to 35-Year-Old Meme